Solutions & treatments

Defensive serum: acting against the premature ageing of sensitive skin

Sensitive skin is often exacerbated by external factors. This weakens the skin’s defences and speeds up premature ageing, known as inflamm’ageing. Through a combination of biomimetic hyaluronic acid and Defensive Technology inspired by ecobiology, Bioderma’s new Sensibio Defensive serum helps strengthen the skin’s natural defence mechanisms and slow premature skin ageing.

External aggressions, such as sudden hot and cold temperatures, pollution, UV rays, stress, make-up, and unsuitable cosmetics, can worsen skin sensitivity. This further aggravates the vicious cycle of sensitive skin, whereby oxidative stress weakens the skin’s protective barrier and leads to inflammation. When chronic, this inflammation decreases communication between cells and accelerates their senescence ('ageing') through a loss of parabiosis (the ability to ‘live together’), further weakening the skin's defences and reducing collagen and elastin production. Skin ageing is accelerated, in a process called inflamm’ageing. The visible effects of this chronic inflammation appear on the skin more quickly than they would during the natural ageing process, leading to wrinkles, dehydration and a dull complexion.

Find out more about sensitive skin and inflamm’ageing.

Dr Miroslav Radman, Biologist and geneticist specialising in inflamm’ageing.

For Dr Miroslav Radman, a biologist and geneticist specialising in inflamm’ageing, the link between chronic inflammation and accelerated skin ageing also provides part of the solution. “Most of the accumulated physiological and morphological defects of individual cells are kept under control by cellular parabiosis. Unfortunately, parabiosis is lost in inflamm’ageing. From these scientific understandings, a key lever to limit chronic inflammation on a daily basis would be to calm it in order to prevent skin inflamm’ageing.”

Find out more about sensitive skin and inflamm’ageing.

Dr Miroslav Radman, Biologist and geneticist specialising in inflamm’ageing.

Adopting an ecolobiogical approach to premature skin ageing

Addressing inflamm’ageing means considering the skin as an ecosystem that needs to be respected and treated in its entirety using biomimetic ingredients, like hyaluronic acid and vitamin E, and physiological pH. Based on this approach, Bioderma has developed a product innovation designed to biologically slow inflamm’ageing. This is the first serum that cares for sensitive and sensitised skin by strengthening its natural self-defence mechanisms and acting against premature ageing.

Sensibio Defensive serum is a long-lasting soothing and moisturising concentrate that helps slow down the premature ageing of sensitive and sensitised skin caused by external irritants. The ecobiological formula restores the natural function of the skin, while slowing premature skin ageing and the exacerbation of sensitivity. The serum breaks the vicious cycle responsible for the aggravation of sensitive skin and premature ageing. Thus, reducing the appearance of wrinkles and fine lines, while increasing radiance and moisturisation.

The synergy of active ingredients in a pre-ageing serum

Sensibio Defensive serum acts on the causes and consequences of premature ageing through a triple action:

Antioxidant protective action Vitamin E and carnosine are powerful antioxidants, to protect the skin against external stressors.

Strengthening the action of the skin barrier Tetrapeptide-10 plays an active role in restoring and strengthening the skin’s barrier function.

Double anti-inflammatory action Red sage polyphenols help regulate chronic inflammation.

This action is reinforced by hyaluronic acid, a biomimetic ingredient that encourages natural hydration. Fucose polymer further enhances these synergies with an immediate and long-term action to prevent chronic inflammation.

Sensibio Defensive Serum is an oil-in-water emulsion. The fresh, milky texture penetrates the skin easily. It is non-greasy, non-sticky, non-oily and fragrance free, providing comfort immediately and over time without irritating sensitive skin.

Proven efficacy on sensitive skin

Sensibio Defensive serum’s instant and long-term effects have been clinically proven by dermatologists during user trials.

Immediate efficacy

82% drop in intense unpleasant sensations*
94% of users experience immediate soothing effect**
81% of users found their skin more radiant**
24h moisturisation***

Use test, clinical evaluation of the soothing effect, on 21 subjects, auto-evaluation
Use test, % of satisfaction, immediate effectiveness on 31 subjects for 28 days
Corneometry test, on 10 subjects and after 24 hours of monitoring

Over time

84% fine lines and wrinkles are reduced*
88% skin is more radiant*
90% skin is strengthened*
93% skin is less sensitive or sensitised*

*Use test, % of satisfaction, on 31 subjects for 28 days

Sensibio Defensive serum as part of a dermatological routine for sensitive skin.

An adapted routine helps soothe sensitive skin and strengthen its natural defences. Using products from a range, like Sensibio, that is created specifically for sensitive skin ensures high levels of tolerance and comfort.

1. Cleanse

Apply Sensibio H2O micellar water or Sensibio Gel moussant micellar cleansing foaming gel. Sensibio H2O eye will remove even the heaviest waterproof eye makeup.

2. Sensibio Defensive serum

Apply Sensibio Defensive serum daily to face and neck.

3. Sensibio Defensive

Apply Sensibio Defensive daily to face and neck.

When combined, Sensibio Defensive serum and Sensibio Defensive, an active soothing cream, increase skin hydration by 100%* and are 24%** more soothing.